Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 101

GL UTIT- PEPTONE SUBLIMA TE.

Respiration.-This alkaloid depresses this function by
acting directly on the respiratory centres.
Temperature.-Large doses lower the temperature
very decidedly.
Pupil.-This drug dilates the pupil by paralysis of the
oculo--motor fibres.
Therapeutic Applications.-This drug is useful as an
antispasmodic and analgesic in the treatment of convul-
sive coughs and neuralgias.
Administration.-Doses of gelsemine vary from 60
to 210- of a grain (o.ooI to 0.003 gramme).
Toxicology.-Among the bad symptoms produced by
this drug may be mentioned the following: dropping of
the jaw; ptosis; languor; drowsiness; great muscular
relaxation; feeble and rapid pulse; moist and cold skin;
anxious face ; loss of voice; slow and labored respiration;
impaired sensibility; disturbed vision, which is some-
times double; dilated pupil; and great fall of bodily
temperature. The treatment in poisoning is general
stimulation with the application of emetics. Ammonia,
digitalis, and strychnia, together with the application of
external heat, may be used.
GLUTIN-PEPTONE SUBLIMATE.
This is a hydrochlorated glutino-peptonate of mer-
cury containing 25 per cent. of corrosive sublimate.
It is obtained by the action of hydrochloric acid on
gelatin.
Physical Properties.-This compound is a white
hygroscopic powder, but it generally occurs as a color-
less non-corrosive liquid.
Therapeutic Applications. This remedy is chiefly
employed as an antisyphilitic.
Administration.-The glutinz-peptone sublimate is best
administered hypodermatically (it does not produce
much pain or form abscesses) in doses of 15 grains
(I gramme).

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