Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 153
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PHE LLANDRIUM.-PHE NA CE TIN
the valerianate, have been tried in practical menicine,
especially the latter one.
Physical Properties.-Pereirine valerianate occurs as
a brown crystalline powder.
Solubility.-This drug is freely soluble in alcohol,
scarcely so in water, and insoluble in ether.
Therapeutic Applications.- Valerianate of pereirine
has been used with asserted good results as an antipy-
retic, especially in diseases of malarial origin.
Administration.-This remedy may be given in pow-
der, in single doses of as high as 30 grains (2 grammes),
a few hours before the expected paroxysm in the inter-
mittent type of the disorder.
PHELLANDRIUM.
This plant, Phellandrium aquaticum, recently intro-
duced into practical therapeutics, has not as yet been
thoroughly studied. Attention has been called, how-
ever, to its medicinal virtues, it having been found to be
of value in diseases of the respiratory tract, such as
bronchitis. It is claimed to be a specific sedative to the
bronchial mucous membrane.
PHENACETIN.
This medicinal agent is a derivative of coal-tar. It is
called also acetphenetidin and phenaceticzum. Its chem-
ical nature is represented by the formula C6H4OC2H,-
NHCH3CO.
Physical Properties.-Phenacetin is a tasteless, in-
odorous powder made up of scaly crystals having a
melting-point of 275 F. (1350 C.).
Solubility.-This drug is soluble in alcohol, more or
less soluble in boiling water, and but sparingly soluble
in cold water and in glycerin. Rectified spirit dissolves
it in the proportion of I to I6 parts.
Physiological Action.-Nervmous System.-The action
of phenacetin on the nervous system is not well known.
There is reason to believe, however, that as a sedativeI53
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/152/: accessed April 25, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.