Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 169
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Q UINOIDIN. -RANDIA.
per cent. of the alkaloid, is represented by the formula
(C20H24N20,)2H C,SO,H,,3 H20.
Solubility.-This remedy is soluble in water in the
proportion of I to I.
Physiological Action.-The action of this double salt
is similar to that of quinine itself.
Therapeutic Applications.- Cl/dor/tydro-sulphate of
quinine has given excellent results as a substitute for the
sulphate or the chlorhydrate. It has been employed
hypodermatically, and is said to be rapidly absorbed.
The injections are, it is assured, painless.
QUINOIDIN.
Quinoidin is a mixture of amorphous alkaloids oc-
curring in the preparation of the active principles of cin-
chona.
Physical Properties.-This mixture occurs as a
brownish-black mass having a nauseous taste.
Solubility.-This drug is soluble in water made
slightly acid.
Therapeutic Applications.- Quinoidin is mainly em-
ployed as a substitute for quinine, and in similar doses.1
RANDIA.
This East-Indian plant (Randia dumetorum) has of
late claimed the attention of physicians as a therapeutic
agent of some value. No thorough chemical study of it
has yet been made, although it is said to contain valeri-
anic acid and a glucosidal principle allied to saponin.
Therapeutic Applications.-Randia has been em-
1 Two salts of quinoidin, the borate and the citrate (the latter appearing
as a brown hygroscopic substance, soluble in alcohol, glycerin, and the
acids, and in hot water in the proportion of I to 2 parts), are also some-
times employed as substitutes for quinine.
From Quinia cuprea an alkaloidal phenol has recently been extracted,
cupreine (C19H21A20O,OII). Two derivatives of this body are termed
quinet/yline (CI 2I,1AzO,0C2-17) and quino-propyline or PropyloLupreine
(C9H21Az2(),OC3117). All these new agents possess antithermic and an-
algesic properties, but have not yet been largely used in practical medicine.I69
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (https://texashistory.unt.edu/ark:/67531/metapth143542/m1/168/: accessed April 25, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.