Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 21
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A GARICIN.-A GA THIN.
This substance is known under various other names,
as agaric, agaricic, agaricinic, and laricic acid. It is
obtained from the Fungus laricis or Polyporus oficinalis,
commonly called white alaric, touchwood, or punk. The
formula of agaricin is C16H00 ,+ H2O.
Physical Properties.-Agaricin is a white powder
with a melting-point of 28o.4 F. (1380 C.).
Solubility.-This drug is only slightly soluble in
Physiological Action. The action of this drug has
not been accurately determined, but in acting as an anti-
hidrotic it is asserted to influence the nerve-filaments of
Therapeutic Applications.-Agaricin has been used
as an antihidrotic in the night-sweats of phthisis, but its
value is somewhat uncertain.
Administration.-This remedy is best given at night,
in pill form, in doses of from 1 to 2 grains (o.064 to
0.128 gramme) every five hours.
Agat/zin is the name of a new drug which chemically
is the salicyl-a-metlzyl-phenyl-lzydrazone, obtained by the
interaction of salicylic aldehyde and a-methyl-phenyl-
hydrazine. It is represented by the formula C6H4(OH).-
CH = N.N(CH3).C6H5.
Physical Properties.-Agathin is a white-greenish
crystalline substance, odorless and tasteless, with a melt-
ing point of 165.2 F. (74 C.).
Solubility.-This drug is soluble in alcohol and ether,
but is insoluble in water.
Therapeutic Applications.-The principal action of
agathin is that of an analgesic and antirheumatic. It
has been tried with satisfactory results in the treatment
of nervous disorders, especially in trigeminal neuralgia
and in sciatica. Good effects have also been observed
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/20/: accessed September 23, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.