Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 25
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Toxicology.-Amylenehydrate in large doses is capa-
ble of producing a very deep narcosis accompanied with
general muscular paralysis, loss of reflexes, dilated
pupils, a small, slow pulse, an irregular, slow, and deep
respiration, and diminished bodily temperature. In cases
of poisoning by this drug general stimulation should be
applied, and, if necessary, artificial respiration.
Analgen, which has recently been introduced into
practical medicine, is a derivative of chinolin. It is
the ortlio-oxyetliyl-anamo-acetyl-amnido-cinolin, and is
represented by the formula C26H4N204.
Physical Properties.--Analgen occurs in the form of
a white powder having a bitter taste. It has a melting-
point of 3110 F. (1550 C.).
Solubility.---This new agent is readily soluble in hot
water, in alcohol, and in the dilute acids. It is almost
insoluble in cold water.
Physiological Action. Analgen is dissolved by the
gastric juice, and appears in the urine in from a half to
one hour after its ingestion. It is broken up in the
stomach into acetic acid and ortho-oxyethyl-ana-amido-
chinolin, the presence of the latter body in the urine
being shown by a reddish tint. A hypodermatic injection
of 15 grains (I gramme) of the sulphate of analgen has
produced convulsions in guinea-pigs. Doses of 45
grains (3 grammes) a day produced no urinary symp-
toms in dogs.
Therapeutic Applications.-This new remedy has
been found to possess valuable antipyretic and analgesic
properties. It is said to be of service in the treatment
Administration.-This drug may be given in doses
of 15 grains (1 gramme).
Anemonine is the alkaloid principle of Anemone
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/24/: accessed September 23, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.