Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 35
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AN TIP YRIN.
on account of its action on the blood and its depressant
effect upon the general circulation, especially the heart.
It is claimed that antipyrin is essentially useful in all
forms of neuralgia, and to a considerable extent in epi-
lepsy. It has also been recommended in chorea, tetanus,
whooping-cough, migraine, locomotor ataxia, hemicrania,
and sciatica. The good effects produced in these ner-
vous disorders is unquestioned, but here, again, the
medicament as a nervine or analgesic should be admin-
istered only to individuals whose blood is more or less
in good condition. Antipyrin has been serviceable in
incontinence of urine, uterine cancer, dysmenorrhoea,
and the pains of labor. It has also proved beneficial in
exophthalmic goitre, nocturnal pollutions, pains of tuber-
cular meningitis, asthma (essential or of cardiac origin),
angina pectoris, distress of aortic aneurism, diabetes
mellitus, cerebro-spinal meningitis, sunstroke, and infan-
tile diarrhoeas. Combined with cocaine, antipyrin has
relieved obstinate vomiting. Similarly, good is said to
have been produced by the drug in skin diseases, such
as urticaria, erythema nodosum, senile pruritus, prurigo,
eczema, and others. Locally applied, antipyrin has been
of service as an analgesic in nasal and throat troubles,
and as a haemostatic in hemorrhages. In the same way
it has been used with excellent results in simple and
granular conjunctivitis, dacryocystitis, episcleritis, scleri-
tis, and chronic glaucoma. It has similarly rendered
great service in purulent otitis and in cystitis with am-
Contraindications.-Aside from cases of blood dis-
orders, such as anemia, chlorosis, etc., the use of the
drug appears to be contraindicated in cardiac affections,
in diphtheritic disease accompanied with myocarditis, in
inflammatory affections of the lungs such as croupous
pneumonia, in advanced tubercular cases, and in exhaus-
tion from hemorrhages.
Toxicology.-Owing to individual idiosyncrasies
antipyrin often causes untoward effects. Among these
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/34/: accessed November 20, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.