Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 42
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42 NOTES OAN THE NEWER REMEDIES.
Aristol is the dithymol-diiodide, also commonly called
" annidalin," but it must not be confounded with the
latter substance, which is the dithymol-triiodide. Aristol
is a substitution-compound from two molecules of thymol
(C10H,3HO) in which the two radicals of hydroxyl (HO)
have been replaced by two iodoxyl radicals (IO0). It is
chemically represented by the formula CH7 C,2(I)-
Physical Properties. Aristol is a reddish-brown
powder, odorless or of a somewhat aromatic odor. It
contains 45.80 per cent. of iodine.
Solubility.-This remedy readily dissolves in ether,
collodion, and traumaticin; it is slightly soluble in
chloroform, but is insoluble in water and glycerin.
Physiological Action.-It is asserted that even in very
large quantities aristol exercises no deleterious influence
on the lower animals. Its antiseptic power is also very
feeble. How the drug is eliminated has not been deter-
Therapeutic Applications.-Aristol has been em-
ployed with success in cutaneous affections and syphi-
litic lesions, as a substitute for iodoform. It is especially
valuable as a cicatrizant in the ulcers of tertiary syphilis,
and good has been obtained from its use in lupus and
psoriasis. It has been found highly serviceable, locally
applied, in the treatment of interstitial keratitis.
Administration.-This drug is generally employed as
a dusting-powder or in the form of an ointment of a
strength varying from 2 to I drachm (I.95 to 3.9
grammes) to the ounce (31.10 grammes) of vaseline.
This substance, recently introduced into the market
and into practical medicine, occurs in acicular crystals.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/41/: accessed August 17, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.