Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 43
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It is the calcium-s -naplztol-a-mono-sulplkonate, with a
formula of (CH.C,,0HSO3)2CA,3Aq.
Solubility.-This drug is readily soluble in water and
Incompatibility.-Asaprol is incompatible with all the
salts that precipitate lime, particularly with the soluble
sulphates and the bicarbonate of sodium; it is also
incompatible with the iodide of potassium and the qui-
Physiological Action.-No extended studies have
been made regarding the general physiological action of
this medicament, but it has been found that it reduces
hyperpyrexia very decidedly. It causes an increase in
the amount of urine secreted. Asaprol appears to be a
powerful antiseptic, solutions of it of the strength of 5
per cent. preventing the growth of the microbes of
Asiatic cholera, the germs of which are destroyed by
stronger solutions of the drug.
Therapeutic Applications.-This remedy is claimed
to have acted most advantageously in acute articular
rheumatism and in acute and subacute polyarticular
rheumatism. As an antipyretic it has been used with
success in typhoid fever, influenza, and pneumonia.
Good results have been observed in acute tonsillitis both
of adults and of children, as well as in the treatment of
boils and in that of infectious diseases accompanied with
albuminuria. In the latter cases the albumen has dis-
appeared from the urine in a short time. As an analgesic
asaprol has been serviceable in sciatica, intercostal neur-
algia, tic douloureux, and the pains of muscular rheu-
matism. Asthma has been relieved by this drug, and
beneficial results have been noticed from its use in rebel-
lious cases of chronic rheumatism.
1 Asaprol must not be mistaken for a recent disinfectant which goes
under the name of saprol. Saprol appears in the form of an oily brown
liquid having an odor of carbolic acid, with a sp. gr. of .o99. It is said to
contain .43 per cent. of phenol, 53.9 per cent. of cresol, and 2.8 per cent.
of hydrocarbons, pyridin, and other bases. Saprol has been employed with
asserted excellent success as a disinfectant, particularly of fecal matters.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/42/: accessed September 20, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.