Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 55
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from 296.6 to 308.8 F. (1470 to 15 0 C.) and solidifies
at 360 F. (2.5 C.); its sp. gr. is 2.83 at 320 F. (o C.).
Solubility.-This drug is soluble in alcohol and ether,
but only slightly soluble in water.
Physiological Action.-Bromoform has general anaes-
thetic properties. Under its influence the respiration is
not affected, but the blood-pressure is lowered. Anaes-
thesia is slowly developed and similarly disappears.
This drug causes great irritation of the conjunctival and
nasal mucous membrane and a diminished irritability of
the cerebral cortex. It is said also to be a powerful
Therapeutic Applications.-Bromoform is powerful
and prompt in its action. It has chiefly been used as an
antispasmodic, analgesic, and antiseptic. This remedy
is of special value in the treatment of whooping-cough.
Locally applied, it has given excellent results in ozaena
and in tuberculous and other ulcers. Bromoform has
been employed as a general anaesthetic, but with little,
if any, success.
Administration.-For children the remedy is best
given in alcoholic solutions, in syrup of acacia, or com-
bined with paregoric, in doses of from I to 5 minims
(o.o6 to 0.30 gramme) three times a day.
The name of tribromophenol is likewise given to the
above drug, and it is prepared by the action of bromine
upon an aqueous solution of phenol. Its chemical com-
position is C6HBr3OH.
Physical Properties.-When pure, bromol occurs as a
white crystalline substance having an astringent sweetish
taste and a disagreeable odor resembling that of bromine.
Bromol melts at 2030 F. (950 C.).
Solubility.-This drug is readily soluble in alcohol,
ether, chloroform, and glycerin, and also in the fatty and
ethereal oils, but is insoluble in water.
Physiological Action.-Bromol is comparatively
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/54/: accessed April 25, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.