Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 58
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58 NOTES ON THE NEWER REMEDIIES.
eliminated in the form of urobutyl-chloralic acid, said to
be analogous to uro-chloralic acid.
Therapeutic Applications.-Butyl-chloral is used as
an analgesic and hypnotic. It is valuable in neuralgias,
and especially in insomnia due to heart trouble. While
useless in toothache, it is said to be of great service in
neuralgia due to decayed teeth.
Administration.-The dose of this medicament is 5
grains (0.30 gramme) every hour, and it may be given
until 30 grains (2 grammes) are taken.
This plant, designated also by the name of Cereus
grandiflora, has recently been investigated, and is said to
contain an alkaloid called cactize. The chemical com-
pos.ition of this active principle has not yet been made
Physiological Action.-Nervous System.-Cactus acts
like strychnine upon the spinal cord, increasing the
reflexes and causing, in sufficiently large amounts, con-
vulsions, chiefly of spinal origin.
Circulation.-This drug elevates the arterial pressure
by acting on the vaso-motor centres and on the cardio-
motor ganglia. The cardiac beat is made stronger and
its rapidity is increased. Large quantities of the drug
diminish both the pulse-rate and the blood-pressure.
Therapeutic Applications.-This plant has been suc-
cessfully employed as a stimulant in diseases of the heart,
especially myocarditis and valvular lesions, as a sutbsti-
tute for digitalis. It seems to be particularly indicated
in cardiac weakness and palpitation. This drug has acted
well in angina pectoris, and it has been used with good
effect also in cardiac dropsy. This remedy is said not
to produce cumulative effects, and it is asserted that no
untoward symptoms have ever been observed under its
influence. It is claimed to be of special value in cases of
severe arrhythmia when other medicaments have failed.
Administration.--Two preparations of this plant are
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/57/: accessed December 13, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.