Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 59
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CAFFEINE TRIIODIDE.-CAL CIUM SALIC YLA TE. 59
in use-the tincture and the fluid extract. Of the first
the dose is from 15 to 20 minims (0.90 to 1.20 grammes),
and of the second 5 to 1o minims (0.30 to o.60 gramme),
three times a day.
Several salts of caffeine have of late claimed recogni-
tion as valuable therapeutic agents, chief among which
is triiodide of caffeine, which is the caffeine di-iodide-
hydro-iodate,' represented by the formula (C18H10N40212-
HI)2 + 3H20.
Physical Properties.-The triiodide of caffeine appears
in long dark-green prisms.
Solubility.-This salt is freely soluble in alcohol.
Therapeutic Applications. This drug, when given
internally, is said to liberate iodine in the stomach. It
is certainly non-depressant, and is employed as a general
heart-tonic, stimulant, and diuretic, especially in cases
of dropsy of cardiac origin.
Administration.-The dose of this medicament may
be set down as from 2 to 4 grains (0.12 to 0.25 gramme).
The chemical composition of this salt is CaC7H403,-
Physical Properties.-Salicylate of calcium occurs as
a white crystalline powder, tasteless and odorless.
Solubility.-This salt is not readily soluble in water.
Therapeutic Applications.- Calcium salicylate is of
special value in the intestinal disorders of children, such
as diarrhea and gastro-enteritis.
1 Carbolate. cinnamylate, boro-citrate, salicylate, and phtalate of caffeine
have been highly recommended for hypodermatic use, owing to their solu-
bility and non-irritating action upon the mucous membranes. Boro-citrate
is said to possess antiseptic properties due to the boric acid. Iodocaffeine,
or sodium and caffeine, has recently been recommended as a heart-tonic, in
daily doses of from 7 to 45 grains (0.5 to 3 grammes) in the form of
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/58/: accessed May 22, 2018), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.