Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 74
This book is part of the collection entitled: Rescuing Texas History, 2010 and was provided to The Portal to Texas History by the University of Texas Health Science Center Libraries .
The following text was automatically extracted from the image on this page using optical character recognition software:
74 NOTES ON THE NEWER 'REMEDII'S.
Colchicine is the active principle of the common
meadow-saffron (Colchicum autumnale), its formula being
Physical Properties.-This drug occurs as an amor-
phous body with a melting-point of from 289.40 to
296.60 F. (143 to 147 C.).
Solubility.-Colchicine is readily soluble in water,
alcohol, and chloroform.
Physiological Action.-This alkaloid resembles the
mother-drug in its action. It is a violent gastro-intes-
tinal irritant, poisonous doses producing great prostra-
tion, vomiting, and severe purging. This drug causes a
period of excitement accompanied by convulsions with
greatly increased reflexes, followed by abolition of reflex
actions and paralysis. The higher nerve-centres, like
the cord and the peripheral sensory nerves, are decidedly
affected by the drug, but the motor nerves as well as the
muscles remain intact. Upon the circulation, the respi-
ration, and the temperature the drug exercises, in mod-
erate amounts, little or no influence.
Therapeutic Applications.-Like colchiceine, the
remedy under consideration has been employed in the
treatment of rheumatism and gout, with alleged success.
It is also recommended in sciatica.
Administration.-The dose of colchicine varies from
rh to 0 of a grain (0.0005 to 0.003 gramme).
The bark of Gonzobolus condurango is said to contain a
glucoside and other active principles.
Therapeutic Applications. Condurango is mostly
used as an alterative in syphilis and cancer. It is also
effective as a stomachic tonic.
Administration.-The only preparation used at
present is the fluid extract, the dose of which is from
20 to 30 minims (1.2 to 2 grammes).
Here’s what’s next.
This book can be searched. Note: Results may vary based on the legibility of text within the document.
Tools / Downloads
Get a copy of this page or view the extracted text.
Citing and Sharing
Basic information for referencing this web page. We also provide extended guidance on usage rights, references, copying or embedding.
Reference the current page of this Book.
Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/73/: accessed June 25, 2018), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.