Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 77
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CON VOL VUL IN.- CORNUTINE.
Solubility.-This drug is soluble in alcohol, but in-
soluble in water.
Physiological Action.-Nausea, diarrhea, and gastric
pain are the chief symptoms produced by convallarin.
Therapeutic Applications.-This medicament has
been used purely for its purgative effects.
Administration.-This remedy is given in doses of
from 2 to 4 grains (o.I2 to 0.24 gramme).
From several plants of the genus Ipomnea, but espe-
cially from Ipomwa purga, is obtained the glucoside
convolvulin. Its chemical formula is C3,,H001s.
Physical Properties.-Convolvulin occurs as an
Solubility.-This glucoside is readily soluble in alco-
hol and in acetic acid; it is insoluble in water.
Therapeutic Applications.-Although the drug pos-
sesses errhine properties, it has chiefly been employed
as an effective purgative.
Administration.-The dose of convolvulin is i to
3 grains (o.o9 to o.18 gramme).
This body is considered the most active constituent
of ergot (Secale cornutum). No chemical analysis of the
drug has been made.
Physical Properties.- Cornutine appears as a brown-
ish-gray amorphous powder; it is said to be an alkaloid.
Solubility.-This alkaloidal remedy is scarcely solu-
ble in water, but its salts, more especially the citrate and
the hydroch/orate, are dissolved by water.
Therapeutic Applications.-This drug is asserted to
be of advantage in hemorrhages from the genito-urinary
organs of both males and females. Although apparently
useless in spasmodic spermatorrhoea, this drug has given
excellent results in the treatment of the ordinary para-
lytic form of the disease.
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/76/: accessed October 20, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.