Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 79
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CR!E OL IN.
Therapeutic Applications.-The only marked value
attributed to cotoin is as an anticholeric, and as such it
is said to exercise a specific action upon the intestinal
mucous membrane. This remedy is alleged also to
check the night-sweats of phthisis.
Administration.-Cotoin is best given in acetic ether,
in which it may be dissolved in the proportion of I to 4
parts. Its dose varies from Y2 to 2 grains (0.03 to 0.12
Creolz, a form of cresol, is obtained from coal-tar.
Physical Properties.-This body appears as a black
alkaline fluid of the consistency of syrup, its sp. gr.
being from 1o40 to Io80. It has a characteristic odor.
Solubility.-Creolin is soluble in alcohol, ether, and
chloroform, and insoluble in wood-spirit; with water it
makes a milky mixture.
Therapeutic Applications.-This remedy is highly
valuable as a general antiseptic and sedative. It is of
special benefit in cystitis and other diseases of the genito-
urinary tract. It has done good service in intestinal
disorders, and has been used, internally administered, with
asserted success against phthisis. Diseases of the eye
and ear have also received benefit from the drug. Creolin
has of late been found beneficial, given by the stomach,
in the treatment of vascular affections such as chlorosis.
This drug is said to be almost a specific in scrofu-
losis and to be of much value in cholera morbus. In
the treatment of the latter disease this drug is added to
the milk used for sucklings, and in this manner this fluid
becomes thoroughly sterilized.
Administration.-When given internally-and this is
best done in capsules-the dose is from I to 5 minims
(o.o6 to 0.3 gramme). For chlorosis and scrofulosis a
daily dose of creolin of from I I2 to 2 drachms (6 to 8
grammes) is recommended. To sterilize milk for chil-
dren suffering from cholera morbus the bottle is first
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/78/: accessed April 25, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.