Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition Page: 88
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88 NOTES OAN THE NEWER REMEDIES.
tion of the automatic cardiac centres; the slowing which
follows depends on a diminished irritability of the cardiac
muscle. This drug has no effect apparently on the vagi,
the cardio-dilator centres, or the peripheral vaso-dilator
Respiration.-Action uncertain, but bromide of ethyl
usually kills by respiratory failure.
Therapeutic Applications.-This drug is employed as
an anaesthetic for cases of minor surgery. The anas-
thesia produced by the drug is prompt, being effected in
the course of from a half to one minute, but soon passes
off after the removal of the remedy. Ethyl bromide is
therefore inferior, from a practical point of view, to
chloroform, but is often preferable to the latter agent.
Administration.-The dose of bromide of ethyl is
from 3 to 6 drachms (I 11.25 to 22.50 grammes), adminis-
tered by inhalation.
Toxicology. Nausea and vomiting sometimes follow
the administration of ethyl bromide. An unpleasant
garlic-like odor of the breath and a similar taste in the
mouth often remain for several days after the use of the
drug. Bromide of ethyl is apt to produce -nervous
twitchings and even tetanic spasms. It has caused death.
This new anaesthetic is said to be produced by the
action of hydrochloric acid upon alcohol. It is repre-
sented by the formula C2,HC1.
Physical Properties.-This drug occurs as a colorless,
inflammable, volatile liquid of a not unpleasant odor.
It boils between 50o and 530 F. (Ioo to I2 C.) and burns
with a green flame.
Physiological Action. This drug acts as a fugacious
general anaesthetic. The anasthesia produced by it,
however, is usually accompanied by a fall of the arte-
rial pressure and a decrease in heart-beat, due probably
to a direct cardiac action. It increases at first both the
rate and depth of the respiratory movements, followed
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Cerna, David. Notes on the Newer Remedies: Their Therapeutic Applications and Modes of Administration, Second Edition, book, 1894; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143542/m1/87/: accessed July 21, 2017), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.