A Treatise on the Eclectic Southern Practice of Medicine Page: 90 of 724
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Massie's Tonic Pill.
n1. Quinine, 3i. 60 grs.
Piperine, ass. 30 "
Podophylline (mandrake), x grs.
Rhubarb, sii. 40 "
Capsicum, Di. 20 "
Oil of black pepper 40 gtts. 40 drops.
Oil of anise, 8 " 8 "
Pulverize this well, and divide into 5 gr. pills. My
usual mode of administering is to commence about six
hours before the paroxysm begins, and give one every
I have frequently used the following compound, and
with the happiest results; whether it has ever before
been introduced to the profession I know not, but from
my own experience I can recommend it as a valuable
remedy. Its action upon the spleen is equ ly effica-
cious as quinine, and without doubt the most valuable
succedaneum to quinine which has yet been discovered.
The article is gentianine, given from 15 to 30 grain
doseh twice a day.
In regard to quinine, frequent objections are raised on
account of its extreme bitter taste. We have tried
Bouchardot's method, and think well of it; he substi-
tutes tartaric acid in lieu of sulphuric acid; it hastens
the solution. M. Casorati has found that one grain of
the tartaric acid is sufficient to saturate three of disul-
phate of quinine, and it is not at all unpleasant to the
Prevention of Ague, says Dr. Elliotson, is to prevent
all accumulation of dead vegetable substance, in order
to prevent as much as possible exhalations from putri-
fled vegetable matter. When land cannot be drained,
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Massie, J. Cam. A Treatise on the Eclectic Southern Practice of Medicine, book, 1854; Philadelphia, Pennsylvania. (texashistory.unt.edu/ark:/67531/metapth143817/m1/90/: accessed March 21, 2018), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.