Dallas Voice (Dallas, Tex.), Vol. 22, No. 41, Ed. 1 Friday, February 24, 2006 Page: 96 of 100
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The skin you re in
Dermagenetics use clients' own DNA to make skin look its youngest
By Joey Guerra Contributing Writer
DNA sampling is nothing new amid the world
of crime scenes and courtrooms. Those tiny bits
of genetic information, however, are also being
used to effectively battle the aging process.
Dennagenetics is a personalized skin-care
product that is customized based on genetic test-
ing that measures single nucleotide polymor-
phisms (SNPs, pronounced "snips") in DNA.
SNPs are natural genetic variations in DNA that
are responsible for why humans differ from one
another. Each person's DNA contains three mil-
Dr. Scott C. Wise is a proponent of
Dennagenetics and recommends it for patients
who have skin damage as well as those seeking
early preventive treatment. It is effective for both
men and women, but not recommended for chil-
dren under the age of 13.
"You think off the top of your head that the
market for this is people who have had
significant sun damage. Certainly,
that's true. It does a great job repairing
damaged skin," Wise says. "It's also \
true, though, that it's almost never too
early to start looking at it, in tenns of pre-
ventive therapy. I have a couple of very
young patients who are using it, too.
It's the young population who is still
doing most of the sunbathing," he adds.
Wise is director of HealthWise Family
Medicine in Frisco and was in private practice for
many years at Medical City Dallas Hospital,
where he served as Chief of Family Practice from
Flealthwise is a full-spectrum medical prac-
tice, but they specialize in chemical peels,
pennanent hair removal, microder-
mabrasion, photo facials, photo rejuve- /
nation and acne photo therapy. Any of
those procedures — coupled with
Dennagenetics' individualized therapy
— makes for a particularly successful
regimen for maintaining skin health,
according to Wise.
"It's pretty well known in the
industry that if you're going to get the
most bang for your buck out of what-
ever procedure you choose — HI
whether it's chemical peels, photofa-
cial, microdennabrasion, whatever —
you have to be supporting those
efforts topically with some sort of
skin-preserving fonnula," he says.
The initial Dennagenetics process
includes swabbing the inside of a per-
son's cheek, after an initial consulta-
tion. The sample is then sealed inside
a bar-coded envelope, sent to a lab
and tested at five gene sites. They
include skin-aging, wrinkling, colla-
gen breakdown, irritation and the
skin's ability to defend against envi-
"They take that infonnation and
kind of mix up your magic fonnula, if
you will, and send that back to us in
a couple of weeks," Wise says.
"Now, you have a very, very cus-
tom-made, topical skin-care fonnu-
Frisco-based Dr. Scott C. Wise specializes in skin treatments.
la to go along with whatever procedures you
might be doing — not that you have to be doing
any. It works just fine by itself"
After that first batch of finning fonnula is con-
cocted, a patients' name and personal infonna-
tion are destroyed so that "confidentiality is
maintained," Wise says. Bar codes are then
used to identify each person for future
After two weeks applying the prod-
uct, Wise says 55 to 60 percent of
patients notice a decrease in facial
lines. After eight weeks, he reports 70
percent of patients noted finner,
Dennagenetics made a splash last
year when it showed up in Academy
1 Award gift bags, but this isn't just a
1 L celebrity luxury. The cost isn't as out-
rageous as you might think. The ini-
tial DNA test and a two-month supply
run about $259. Two-month supplies
thereafter cost $159 — in line with the
catch-all effectiveness of most major-
"The people who are active and
interested in either preserving skin or
trying to repair damage that's been
done are the same people who typical-
ly are shopping for the products that
they're using currently at Neiman's
and Nordstrom," Wise says. "The
topical products that they're buying
can easily run 100, 200 bucks a
piece. The niche with
Dennagenetics, obviously, is that it is
manufactured individually for each
For more information, xisit
Dermagenetics skin cream is
customized to each user's
B16 I dallasvoice.com ! 02.24.06
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Vercher, Dennis. Dallas Voice (Dallas, Tex.), Vol. 22, No. 41, Ed. 1 Friday, February 24, 2006, newspaper, February 24, 2006; Dallas, Texas. (texashistory.unt.edu/ark:/67531/metapth238897/m1/96/: accessed June 25, 2018), University of North Texas Libraries, The Portal to Texas History, texashistory.unt.edu; crediting UNT Libraries Special Collections.