Investigations into the Nature, Causation, and Prevention of Texas or Southern Cattle Fever Page: 169
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TRANSMISSION OF TEXAS FEVER.
169
from St. Marys County, Md., and kept in field IV until September 14. On this day
transferred to field III (Southern cattle with ticks).
The animal manifested no symptoms of disease during exposure. On November 5
the blood was examined and no abnormal elements observed. The corpuscles num-
bered 6,000,000. The animal was in very good condition. (For temperature record,
see p. 272.)
1NTo. 40 (Southern).-Steer, 3 years old; received June 27, 1889, from near New Berne,
N. C., and placed in field I. Removed and sold August 17.
No. 41 (native).-Roan cow, 4 years old; received and kept with No. 35 until Sep-
tember 14, 1889. On this day exposed in field IV (Southern cattle without ticks).
On November 6 the blood was examined. No abnormal forms observed. The
corpuscles numbered 6,520,000. (For temperature record, see p. 273.)
No. 42 (Southern).-Cow, 6 years old; received June 27, 1889, from near New Berne,
N. C., and placed in field I (North Carolina cattle with ticks).
August 17-Removed and sold.
No. 43 (native).-Red steer, about 3 years old, from Charles County, Md. Placed
in field I (North Carolina cattle with ticks) August 24, 1889.
September 10.-Urine collected to-day has a port-wine color. Reaction alkaline.
Liberation of large quantities of gas when acidified. When boiled it remains clear
until an acid is added, when a brownish flaky precipitate forms, which, after settling
over night, is equivalent to about one-sixth of the column of liquid in test tube.
September 11.-Animal very weak towards evening, lying down most of the time.
Continues in this condition for another day, and is found dead on the morning of
September 13. Examined immediately.
Autopsy: On the surface of the heart some small blood extravasations. Small, firm,
dark-red clots in both cavities of the heart.
Slight hypostatic congestion of the right lung; no lesions observable.
Spleen very large (21 X 7 X 14 inches), soft, dark-colored. In fresh and stained
preparations of spleen pulp a moderate number of round, intraglobular bodies.
Liver of a yellowish color; the bile-canaliculi more or less occluded with cylin-
drical masses of yellow bile, as in preceding cases. There is also a considerable
amount of fat in the hepatic cells. A preparation from the blood in the liver showed
probably 10 per cent of the corpuscles infected with parasites. Bile contains a dense
suspension of minute yellow flakes.
The bladder contains a liter of clear wine-colored urine without sediment; slightly
acid; specific gravity, 1013. A precipitate forms with picric acid as well as on boil-
ing.
The digestive tract normal, with exception of the duodenum, the mucosa of which
is considerably pigmented and bile-stained. In the rectum the feces covered with
mucus.
Cultures were made from this animal as follows:
A minute bit of spleen pulp was placed in four tubes containing respectively bouil-
lon-peptone, blood serum (cattle), glycerin agar, simple agar. These tubes, kept
under observation in a thermostat for several weeks, remained sterile.
Blood taken from the heart with pipette was added to tubes containing the same
media, 4 cc. being used for each tube. These also remained sterile.
From the kidney bits of tissue were added to the same media. Two tubes con-
tained subsequently a large bacillus with terminal spore; one contained a colony of
yellow coccus, and one a colony of a large coccus. These were probably contamina-
tions. (For the temperature record, see pp. 270 and 271.)
No. 44 (native).-Black and white steer, 4 years old, from Charles County, Md.,
placed in field I (North Carolina cattle with ticks), August 24, 1889.
September 13.-Urine observed to be tinged with hemoglobin to-day (red water).
It behaves towards reagents precisely like that from the preceding case, No. 43.
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Smith, Theobold & Kilborne, Fred Lucius. Investigations into the Nature, Causation, and Prevention of Texas or Southern Cattle Fever, book, 1893; Washington D.C.. (https://texashistory.unt.edu/ark:/67531/metapth143538/m1/189/: accessed July 16, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting University of Texas Health Science Center Libraries.