OncoLog, Volume 55, Number 9, September 2010 Page: Front Cover
8 p. : ill.View a full description of this periodical.
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A Publication of
MD Anderson
Cancer Center
Making Cancer History"Non-Hodgkin
Lymphomas
New targeted therapies
are being testedHouse Call
Cancer patients
may benefit from
keeping a journalTexas State Documents
Collection
In Brief
Abnormal cells in
blood ir iase with
cancer stateREPORT TO PHYSICIANS
C
SEPTEMBER 2010 VOL. 55, NO. 9
-J
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Tiny Particles
trtuor cells, bypassing
By Sunita Patterson
anotech NON-C
noogy U OF N
has be-
come a
buzzword in the en-
ergy, computing,
and fabrications
fields. And now the
potential use of nan-
otechnology in can-
cer therapy is also
rapidly advancing.
The advances builder
on our emerging un-
derstanding of the
molecular attributes
of particular tumors Gold nanoparticles, shown h
and our growing transmission electron microscope
ability to target and with near-infrared light. Reprint
even manipulate Clin Cancer Res
those attributes. Therapies at the nano
scale-in particular, those using nanoparticles
-may enable a new precision and specificity
in targeting tumor cells.
(L-1t _ U O, Vast Potential
noparticles that delive
normal cells and manI RCULATING
T LIBRARIEShere in a mouse melanoma cell by
py, can kill cancer cells when heated
ed with permission from Lu W, et al.
2009;15(3) :876-886.F N
is a millionth of a millimeter);r
range of 5-200 nm. At that
size, the particles are small
enough to evade uptake by the
4T (Continued on page 2r therapy
y toxic effects
At The University
of Texas MD Anderson
Cancer Center, investiga-
tors are working on nan-
otherapies from many
different perspectives.
Nanoparticles are being
made of gold, biodegrad-
able lipids, chitosan, and
various other materials.
Nanoparticles are being
tested as vehicles for drugs,
as packages for gene thera-
py, or as anticancer wea-
pons themselves, activated
at just the right time using
radio waves or near-infra-
red light. And within the
next year or two, several
of these therapies will be
available to patients in
clinical trials. We high-
light a few of the develop-
ing therapies here.
The blueprint
Nanoparticles are so
small they are measured in
nanometers (a nanometer
many have diameters in theTHE UNIVERSITY OF TEXAS
MDAnderson
&65Ater)
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University of Texas M.D. Anderson Cancer Center. OncoLog, Volume 55, Number 9, September 2010, periodical, September 2010; Houston, Texas. (https://texashistory.unt.edu/ark:/67531/metapth903752/m1/1/: accessed July 17, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting UNT Libraries Government Documents Department.